Patients who abuse cigarettes or e-cigarettes containing etomidate, metomidate, or other GABAA receptor agonists
Conditions
Interventions
Substance users (Etomidate or other GABAA receptor agonists):None
Healthy controls:None
Sponsors
Affiliated Kangning Hospital of Ningbo University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Etomidate/metomidate abuser group: Patients who misuse cigarettes or e-cigarettes containing etomidate, etomidate, or other GABAA receptor agonists; 2.those who have previously misused other drugs must have abstained from using such drugs for over three years and currently exhibit no symptoms related to those drugs. There are no gender restrictions. Age is 18 years or older. Education is primary school or higher. (2) Healthy control group: Age is 18 years or older. Sex and education are matched with the etomidate/metomidate abuser group.
Exclusion criteria
Exclusion criteria: (1) Etomidate/metomidate abuser group: with other substance abuse; with other severe neurological or psychiatric disorders; with severe physical illnesses; with severe intellectual or emotional disabilities that prevent cooperation with testing. (2) Healthy control group: a history of severe neurological or psychiatric disorders; with severe physical illnesses; having alcohol use disorders or consuming more than 20g of alcohol daily; with mild cognitive impairment or depressive symptoms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Point of subjective equality;EEG signals; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cross-Frequency Coupling Analysis of EEG signals;Causality Analysis of EEG signals;Just-noticeable difference; | — |
Countries
China
Contacts
Public ContactWenwen Shen
Affiliated Kangning Hospital of Ningbo University
Outcome results
None listed