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Cognitive function intervention and brain mechanism study of severe mental disorders

Cognitive function intervention and brain mechanism study of severe mental disorders

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094838
Enrollment
Unknown
Registered
2024-12-29
Start date
2024-10-08
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe Mental Disorders

Interventions

Experimental group:The intervention group used computer cognitive correction training (CCRT) for 20 sessions of cognitive training, 30 minutes a day, 5 days a week, for 4 weeks. Multiple doses of oxyt
Control group:The duration and frequency of the intervention was the same as in the experimental group, but the nasal spray was replaced with saline, and the cognitive training was replaced with watch

Sponsors

First Hospital of Shanxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Meet the DSM-5 diagnostic criteria for major mental disorders (including schizophrenia, bipolar disorder, and major depressive disorder); (2) Age 18~60 years old; (3) Gender is not limited; (4) Han nationality; (5) right-handed; (6) The subject understands and voluntarily signs informed consent, and is able to cooperate with the completion of various tasks in this study.

Exclusion criteria

Exclusion criteria: (1) Do not meet the DSM-5 diagnostic criteria for major mental disorders (including schizophrenia, bipolar disorder, and major depressive disorder); (2) severe mental disorders combined with other mental illnesses; (3) The woman is pregnant or lactating or has a pregnancy plan in the next six months; (4) Suffering from severe unstable physical diseases or other eye diseases such as color blindness and glaucoma; (5) Unable to accurately understand the content of the mental health rating scale in the study or complete computer operation.

Design outcomes

Primary

MeasureTime frame
Cognitive function;Clinical symptom index;Electrophysiology, eye movement and brain imaging indicators;Blood related index;

Secondary

MeasureTime frame
Social psychology;

Countries

China

Contacts

Public ContactSha Liu

First Hospital of Shanxi Medical University

liusha1984114@163.com+86 351 463 9021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026