chronic kidney disease
Conditions
Interventions
Control Group :Control Group: Routine hemodialysis treatment.
Treatment Group A :Treatment Group A: Low-dose group, 150 mg per day.
Treatment Group B:Treatment Group B: High-dose group, 225 mg per day.
Sponsors
Huashan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Gender: unrestricted; age > 18 years. 2. Maintenance hemodialysis patients with a dialysis duration of =6 months and =12 dialysis sessions, with minimal or no urine output. 3. Presence of pruritus caused by eczema or dermatitis. 4. No use of antibiotics within two weeks prior to enrollment, with a consistent diet maintained. 5. No history of nephrotic syndrome or cholestasis (as such patients have been shown to exhibit reduced 11ß-hydroxysteroid dehydrogenase activity).
Exclusion criteria
Exclusion criteria: 1. Patients who have recently taken probiotics. 2. Patients aged between 0 and 18 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TMAO; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Biochemical Electrolytes; | — |
Countries
China
Contacts
Public ContactXue Jun, Wu Yuanhao
Huashan Hospital Affiliated to Fudan University
Outcome results
None listed