chronic venous disease
Conditions
Interventions
Chronic venous disease group:None
No chronic venous disease group:None
Sponsors
Department of ultrasound of the First Afiliated Hospital of the Air Force Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Experimental group (1) Transvascular Doppler ultrasonography of the lower limbs meets the diagnostic criteria for CVD, or there are symptoms related to CVD but no cases of venous reflux (C0s); (2) Symptoms of lower limb varicose veins, including lower limb edema, tortuous dilation of superficial veins, skin pigmentation, sebum sclerosis, circumferential varicose veins in the ankle area, etc.; (3) The reflux type conforms to one or more of the superficial vein (As), deep vein (Ad) or perforating vein (Ap) in the CEAP anatomical type; or there is no venous reflux but the clinical manifestations conform to the CEAP clinical classification, right Patients with abnormal cardiac function; (4) Meet the diagnostic criteria for primary Ep venous reflux Pr cases in the CEAP classification; 2) Control group: no venous reflux, normal right heart function, and no clinical manifestations or symptoms related to CVD.
Exclusion criteria
Exclusion criteria: 1. Experimental group: (1) Deep vein thrombosis of the lower limbs, thrombophlebitis and other diseases (Caprini score >= 3 points); (2) History of lower limb vascular surgery and sclerotherapy injection; (3) Peripheral artery disease; (4) Severe leg infection; (5) Combined with serious systemic diseases; (6) Pregnant or lactating women and patients with lower limb paralysis; (7) Lower limb aneurysm; (8) Combined with III-IV degree deep venous valve insufficiency or congenital venous malformation and osteohypertrophy syndrome (K?T syndrome), etc.; (9) Patients with severe cardiopulmonary dysfunction; 2. Control group: the same as the experimental group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vein diameter;reflux time;peak and mean reflux velocity;VCSS score;HASTI score;CEAP classification;Tricuspid early inflow velocities;Tricuspid late inflow velocities;Tricuspid early annular velocities;Tricuspid late annular velocities;Tricuspid systolic annular velocities;inferior vena cava diameter; | — |
Secondary
| Measure | Time frame |
|---|---|
| total reflux volume;BMI,Height body mass index;Mitral early inflow velocities;Mitral late inflow velocities;Mitral early annular velocities;Mitral late annular velocities;Mitral systolic annular velocities;hepatic vein flow speed;size of heart atrium; | — |
Countries
China
Contacts
Public ContactYongfeng Zhao
the first affiliated hospital of the fourth military medical university
Outcome results
None listed