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Construction and Validation of a Prediction Model for Early Aspiration Risk in Patients Undergoing Esophageal Cancer Surgery

Construction and Validation of a Prediction Model for Early Aspiration Risk in Patients Undergoing Esophageal Cancer Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094744
Enrollment
Unknown
Registered
2024-12-26
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

Gold Standard:The definition of aspiration is when a patient is found to have swallowed contrast medium entering the trachea or bronchi during digital X-ray imaging of the pharynx, esophagus, and gast
Index test:The patients were divided into a modeling set and a validation set, and univariate and multivariate analyses were conducted on the data from the modeling set to construct the model.

Sponsors

Medical Ethics Committee of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Patients aged >=18 years old; (2) Patients diagnosed with esophageal cancer by pathological examination; (3) Patients undergoing surgical radical esophagectomy (including traditional open esophagectomy, minimally invasive esophagectomy, robotic-assisted esophagectomy); (4) Patients who underwent digital X-ray pharyngeal, esophageal, and gastric cardia in the early postoperative period.

Exclusion criteria

Exclusion criteria: (1) Patients with esophageal cancer combined with gastrointestinal tumors who require modified surgery; (2) Patients diagnosed with precancerous esophageal cancer and diseases that cause swallowing disorders: Parkinson's, severe mental disorders, and oral tumors; (3) Patients who have previously undergone head, neck, laryngeal surgery, gastrointestinal resection or tracheostomy; (4) Patients with confirmed anastomotic leakage after surgery; (5) Patients who lack complete information.

Design outcomes

Primary

MeasureTime frame
Postoperative incidence of aspiration;

Secondary

MeasureTime frame
Model sensitivity;Specificity;Accuracy;Decision curve;

Countries

China

Contacts

Public ContactYushuang Su

Sichuan Academy of Medical Sciences – Sichuan Provincial People's Hospital

244354221@qq.com+86 187 8227 4142

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026