Skip to content

Exploratory clinical study on the efficacy and safety of Romiplostim combined with or without TPO-RAs of cancer treatment-induced thrombocytopenia

Exploratory clinical study on the efficacy and safety of Romiplostim combined with or without TPO-RAs of cancer treatment-induced thrombocytopenia

Status
Active, not recruiting
Phases
Phase 2
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094696
Enrollment
Unknown
Registered
2024-12-26
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CTIT

Interventions

Ropristine in combination with or without small molecule thrombopoietin receptor agonist group:None

Sponsors

Sheyang County People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. The patient signs an informed consent form, voluntarily joins this study, and has the willingness and ability to cooperate with data collection in this study; 2. Diagnosed with malignant tumor and currently undergoing anti-tumor treatments such as chemotherapy, radiotherapy, immunotherapy, and targeted therapy, with PLT<75 × 10^9/L during treatment; 3.Romiplostim was prescribed for the first time at the time of inclusion (Romiplostim was prescribed at the discretion of the supervising physician and was not affected by this study.

Exclusion criteria

Exclusion criteria: 1. The patient is currently undergoing or planned to be enrolled in a clinical intervention study; 2. Unable to understand the nature of the research or without obtaining informed consent; 3. Researchers determine other situations that are not suitable for inclusion in the study.

Design outcomes

Primary

MeasureTime frame
Proportion of patients who respond within 7 days of treatment;

Secondary

MeasureTime frame
Platelet count changes during treatment;Proportion of subjects whose PLT recovered to =75×109/L within 14 days of treatment;The time of platelet recovery to =75×109/L and 100×109/L during treatment;Adverse reaction;

Countries

China

Contacts

Public ContactLei Xing

Sheyang County People's Hospital

xysy2006@189.cn+86 189 6196 8597

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026