Painless diagnosis and treatment of pediatric gastrointestinal endoscopy
Conditions
Interventions
one:Ciprofol group( Group C): After infusing 10µg/kg of afentanil, 0.4/0.2 mg/kg of ciprofol injection was administered through intravenous.That means the first dose is 0.4 mg/kg. The injection was m
two:Propofol group (Group P): After infusing 10µg/kg of afentanil, 2/1mg/kg of propofol was given.That means the first dose is 2mg/kg. The patients reaction was observed manually for 30 seconds, until
Sponsors
Hunan Children's Hospital
Eligibility
Sex/Gender
All
Age
3 Years to 14 Years
Inclusion criteria
Inclusion criteria: (1) Age range from 3 to 14 years old, regardless of gender; (2) American anesthesiologist classification (ASA) I-II; (3) Patients who choose to undergo painless gastroscopy and/or colonoscopy for diagnosis and treatment; (4) Body mass index (BMI) = 18 and = 30kg/m2; (5) Vital signs: respiratory rate = 10 and = 30 times/minute; Blood oxygen saturation (SpO2) = 95% when breathing air; Systolic blood pressure (SBP) = 80mmHg and = 140mmHg; Diastolic blood pressure (DBP) = 40mmHg and = 90mmHg; Heart rate = 55 and = 120 beats per minute; (6) The guardian understands the process and methods of this study and voluntarily participates in it.
Exclusion criteria
Exclusion criteria: (1) Individuals with contraindications to general anesthesia or a history of anesthesia accidents in the past (2) Individuals who are known or suspected to have allergies or contraindications to propofol, excipients for propofol injection, or opioid drugs (3) Patients with acute upper respiratory tract infections, asthma attacks, or airway obstruction (4) Gastrointestinal retention, active bleeding, possible reflux and aspiration, etc (5) Dysfunction of important organs such as heart, brain, liver, and kidney (6) Researchers believe that subjects with any other unfavorable factors to participate in this trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of Gastrointestinal endoscopy ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of Successful Anesthetic Induction; | — |
Countries
China
Contacts
Public ContactShili Zhu
Hunan Children's Hospital
Outcome results
None listed