carotid artery atherosclerotic stenosis
Conditions
Interventions
Fractional Flow Reserve,FFR:NA
Sponsors
Ordos Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Moderate to severe stenosis of the internal carotid artery (50%-99%) and confirmed by DSA examination; (2) Age> 18 years old; (3) The etiology is considered atherosclerosis, and there are risk factors for atherosclerosis, including hypertension, hyperlipidemia, diabetes, coronary heart disease, obesity and smoking, etc.; (4) Not treated with endovascular stenting. (5) The subject himself or legal representative is able to sign the informed consent form
Exclusion criteria
Exclusion criteria: (1) Multiple moderate to severe stenosis of intracranial arteries and extracranial arteries (>50%); (2) Extremely tortuous cerebrovascular lesions (guidewires cannot be operated); (3) There is an aneurysm lesion at the proximal or distal end of the stenotic lesion, which is cardiogenic embolic evidence; (4) Patients with a history of contrast allergy or renal failure; (5) pregnancy; (6) Chronic occlusion, tandem stenosis, and poor angiography image quality and hindering high-quality QFR analysis or the technical parameters of the CTP; (7) Severe overlap or distortion of target blood vessels; (8) patients who cannot obtain informed consent; (9) Contrast-enhanced MRI or CT examination is contraindicated (pacemaker, metal implant into, severe claustrophobia, pregnancy pregnancy, allergy, or glomerular filtration rate <30 mL/min/1.73 m^2); (10) Presence of contraindications to heparin, aspirin or other antiplatelet drugs; (11) Presence of non-atherosclerotic intracranial vascular lesions, such as arterial clips layers, vasculitic lesions, smoke sickness, etc.; (12) The expected survival time of the patient < 2 years; (13) Presence of cranial tumor, atrial fibrillation, aortic stenosis, and aorta Dissection, aortic aneurysm and other risks and diseases of vital organs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fractional Flow Reserve,FFR;Quantitative Flow Ratio,QFR;Radial wall strain,RWS; | — |
Countries
China
Contacts
Public ContactWu Yinchun
Ordos Central Hospital
Outcome results
None listed