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A prospective specific cohort study to investigate the phenotype of lung cancer and its association with clinical, imaging, and biological factors

A prospective specific cohort study to investigate the phenotype of lung cancer and its association with clinical, imaging, and biological factors

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094662
Enrollment
Unknown
Registered
2024-12-25
Start date
2024-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Subjects with pulmonary nodules:None
Subjects with non-small cell lung cancer:None

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Lung cancer subjects A subject with lung cancer met the admission criteria for this study if all of the following criteria were met: 1. Sign a written informed consent prior to the implementation of any trial related procedures; 2. Male or female subjects aged >=18 years and =100 cigarettes) or never smokers (lifetime exposure =18 years of age and =100 cigarettes) or never smokers (lifetime exposure =18 years of age and <=75 years of age with no significant disease in their medical history, physical examination and screening tests; 3. Chest low-dose spiral CT showed no pulmonary nodules; 4. Never smoked (lifetime exposure < 100 cigarettes). Passive smokers don't meet the criteria. 5. No serious organ dysfunction or mental illness.

Exclusion criteria

Exclusion criteria: Lung cancer subjects A subject with lung cancer did not meet the admission criteria for this study if any of the following criteria were met: 1. a known respiratory disease other than lung cancer (e.g., sarcoidosis, active tuberculosis, pulmonary fibrosis, cystic fibrosis) or a disease that, in the investigator's judgment, may significantly affect clinical evaluation at the time of the screening period/visit (including the first pathological diagnosis); 2. Currently participating in interventional clinical research treatment; 3. Known past cancer other than lung cancer (e.g., colorectal cancer, liver cancer, etc.); 4. Have a serious, uncontrollable illness (including serious illness) that could interfere with the study or affect the safety of the subject Mental illness); 5. A history of alcohol or drug abuse as determined by the investigator; 6. Can't walk; 7. No ability to read and understand Mandarin; 8. The presence of medical history, illness, treatment, or experiment that may interfere with the results of the study or prevent the subject from participating fully in the study Abnormal results, or the investigator believes that participation in the study is not in the subject's best interest; Local or systemic disease caused by non-malignant tumors, or secondary reactions to cancer, and may lead to higher medical risk Risk and/or life assessment uncertainty. Pulmonary nodule subject: Subjects with pulmonary nodules did not meet the admission criteria for this study if any of the following criteria were met: 1.a known respiratory disease other than lung cancer (e.g., sarcoidosis, active tuberculosis, pulmonary fibrosis, cystic fibrosis) or a disease that, in the investigator's judgment, may significantly affect clinical evaluation at the time of the screening period/visit (including the first pathological diagnosis); 2. Currently participating in interventional clinical research treatment; 3. Known past cancer other than lung cancer (e.g., colorectal cancer, liver cancer, etc.); 4. Have a serious, uncontrollable illness (including serious illness) that could interfere with the study or affect the safety of the subject Mental illness); 5. A history of alcohol or drug abuse as determined by the investigator; 6. Can't walk; 7. No ability to read and understand Mandarin; 8. The presence of medical history, illness, treatment, or experiment that may interfere with the results of the study or prevent the subject from participating fully in the study. Abnormal ventricular results, or the investigator determines that participation in the study is not in the subject's best interest. Healthy subjects: The healthy volunteer did not meet the entry criteria for this study if any of the following criteria were met: 1.a known respiratory disease other than lung cancer (e.g., sarcoidosis, active tuberculosis, pulmonary fibrosis, cystic fibrosis) or a disease that, in the investigator's judgment, may significantly affect clinical evaluation at the time of the screening period/visit (including the first pathological diagnosis); 2. Currently participating in interventional clinical research treatment; 3. Known past cancer other than lung cancer (e.g., colorectal cancer, liver cancer, etc.); 4. Have a serious, uncontrollable illness (including serious illness) that could interfere with the study or affect the safety of the subject Mental illness); 5. A history of alcohol or drug abuse as determined by the investigator; 6. C

Design outcomes

Primary

MeasureTime frame
Overall Survival;

Secondary

MeasureTime frame
Disease control rate;Safety;Effectiveness;

Countries

China

Contacts

Public ContactSu Wenmei

Affiliated Hospital of Guangdong Medical University

suwenmei123@hotmail.com+86 138 2252 3922

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026