None
Conditions
Interventions
Experimental group:Oliceridine is administered intravenously before the surgery, followed by 2.5 mg/kg of propofol.
Sponsors
The Cixi People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.American Society of Anesthesiologists (ASA) physical status I or II. 2.Aged 18 to 55 years. 3.Body mass index (BMI) between 18 and 25 kg/m^2. 4.diagnosed by a gynecologist as needing hysteroscopic examination.
Exclusion criteria
Exclusion criteria: 1.Patients with a history of severe cardiac, cerebral, pulmonary, hepatic, renal, or metabolic diseases;2.Heart rate 180 mmHg] or hypotension (SBP <90 mmHg);5.Known allergies to emulsions or opioids.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ED50 and ED95 of oliceridine for suppressing response to cervical dilation; | — |
Secondary
| Measure | Time frame |
|---|---|
| The occurrence of adverse reactions;Times of body movement;Time to full alertness;Sedative drug total dosage; | — |
Countries
China
Contacts
Public ContactJiliang He
The Cixi People's Hospital
Outcome results
None listed