Placenta Accreta Spectrum
Conditions
Interventions
mild PAS group:None
severe PAS group:None
Non PAS control group:None
Sponsors
Changzhou Maternal and Child Health Care Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age over 18 years old; 2. Non invasive DNA testing was performed at Changzhou Maternal and Child Health Hospital, Nanjing Maternal and Child Health Hospital, and Nantong Maternal and Child Health Hospital at 12- 26+ 6 weeks of pregnancy; 3. There are high-risk factors for Placenta Accreta Spectrum, such as a history of previous PAS, scarred uterus (previous history of cesarean section, myomectomy and other uterine surgeries), history of hysteroscopy surgery, history of uterine cavity operation (curettage, induced abortion, etc.), and conception via IVF-ET;
Exclusion criteria
Exclusion criteria: 1. Non live birth pregnancy outcomes such as stillbirth and neonatal death; 2. Fetal chromosomal abnormalities or structural developmental abnormalities; 3. Multiple gestations;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area Under the Curve;plasma cfDNA promoter coverage;plasma protein;plasma metabolites;Placental adhesion and implantation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Accuracy;Sensitivity;Specificity;Postpartum blood loss; | — |
Countries
China
Contacts
Public ContactZhonghua Shi
Changzhou Maternal and Child Health Care Hospital
Outcome results
None listed