Asthma for Preschool Children
Conditions
Interventions
Gold Standard:1. Recurrent wheezing, coughing, and shortness of breath, mainly due to exposure to allergens, physicochemical irritation, infection, and hyperventilation, which are more obvious in the
2. Diffuse wheezing and prolonged expiratory phase can be found on examination at the time of seizure
3. The corresponding symptoms are significantly relieved or disappeared after anti-asthma treatment
4. Exclude wheezing and cough caused by other causes
5. Patients with atypical symptoms (such as wheezing is not obvious) should meet at least one of the following: (1) Airflow limitation is found on examination: a. Bronchodilator obstruction: FEV1 incr
b. Improvement of lung ventilation level after anti-inflammatory intervention: FEV1 increased by no less than 12% after 4 weeks of glucocorticoid intervention
(2) positive bronchial challenge, (3) PEF diurnal variability rate > = 13%.
6. Those who meet the first 4 or 4 or 5 of them can be diagnosed with asthma.
Index test:The pulse oscillation spirometer from Jaeger, Germany, was used for the testing, following the standards of the European Respiratory Society.
The instrument used for measurement was the Na
Sponsors
Department of Pediatrics, First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
3 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1) Age 3~6 years old (excluding 6 years old), gender is not limited; 2) Recurrent episodes of wheezing, coughing, shortness of breath, chest tightness; 3) No imaging abnormalities such as chest X-ray, no use of bronchodilators, no oral or inhaled anti-allergic drugs and hormone drugs 3 days before the first outpatient visit; 4) There was no upper respiratory tract infection 4 weeks before the first outpatient visit, and no symptoms such as fever and sore throat were observed.
Exclusion criteria
Exclusion criteria: 1) Suffering from chronic respiratory diseases, such as special pathogen infection, bronchiectasis, and congenital dysplasia of bronchopulmonary disease; 2) Suffering from other complications, such as congenital heart disease, chest deformity, epilepsy, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Impulse oscillometry (IOS) ;Fractional exhaled nitric oxide((FeNO); | — |
Countries
China
Contacts
Public ContactYing Hu
The First Hospital Affiliated to Army Medical University
Outcome results
None listed