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Investigation of Low-Dose and Ultra-Low-Dose CT Imaging for Pulmonary Nodules and Emphysema in Patients with Varying BMI

Investigation of Low-Dose and Ultra-Low-Dose CT Imaging for Pulmonary Nodules and Emphysema in Patients with Varying BMI - Ultra-Low-Dose CT Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094622
Enrollment
Unknown
Registered
2024-12-25
Start date
2024-11-06
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Nodules and Emphysema

Interventions

Standard-dose CT:Standard-dose CT scan: 100kvp smart MA 200-1080, NI: 10
Low/ultra-low dose CT scan:According to BMI (L:BMI < 18.5 kg/m2
M:18.5 kg/m2 = BMI < 24.0 kg/m2
H:24.0 kg/m2 = BMI < 28.0 kg/m2
F: low-dose CT scan with BMI = 28.0 kg/m2): 100Kvp from 25 mAs to 20 mAs or less in L group, 35 mAs to 30 mAs or less in M group, 45 mAs to 35 mAs or less in H group, and 55 mAs to 40 mAs or less in F

Sponsors

Panyu Central Hospital, Affiliated to Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (a) Individuals aged 18 years or older; (b) Presence of a clear image with no motion artifacts or metallic artifacts; (c) Voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: (a) Poor image quality caused by motion or breathing artifacts; (b) The image reconstruction sequence is incomplete; (c) The number of pulmonary nodules on standard-dose CT>=50 patients.

Design outcomes

Primary

MeasureTime frame
Lung nodule size (maximum long-axis diameter);Lung nodule volume;Detection rate of pulmonary nodules;

Secondary

MeasureTime frame
Location of pulmonary nodules;Type of nodule;Nodule weight;CT mean of nodules;Nodule compactness;Nodule sphericity;Maximum layer area of nodules;Probability of malignant nodules;Lung-RADS;Image signal-to-noise ratio(SNR);Contrast-to-noise ratio(CNR);Image noise values in patients with emphysema;Emphysema index;Total lung volume (TLV);Mean dose of lung attenuation;

Countries

China

Contacts

Public ContactXiang Zhiming

Panyu Central Hospital, Affiliated to Guangzhou Medical University

xzmgz@126.com+86 136 6029 2624

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026