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The association between perioperative oral benzodiazepine receptor agonists and postoperative delirium in Parkinson's disease patients undergoing general anesthesia for deep brain stimulation: A retrospective cohort study

The association between perioperative oral benzodiazepine receptor agonists and postoperative delirium in Parkinson's disease patients undergoing general anesthesia for deep brain stimulation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094616
Enrollment
Unknown
Registered
2024-12-25
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease

Interventions

benzodiazepine receptor agonist group (perioperative oral benzodiazepine receptor agonist):None
benzodiazepine receptor agonist group (without orally benzodiazepine receptor agonist during the perioperative period):None

Sponsors

The First Affiliated Hospital, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with Parkinson's disease undergoing bilateral subthalamic nucleus deep brain electrode implantation under general anesthesia in the First Affiliated Hospital of Sun Yat-sen University from March 1, 2018 to February 28, 2023

Exclusion criteria

Exclusion criteria: 1. Patients with vital missing follow-up data 2. Patients with a history of craniocerebral surgery

Design outcomes

Primary

MeasureTime frame
postoperative delirium;

Secondary

MeasureTime frame
the incidence of a composite of other postoperative complications;

Countries

China

Contacts

Public ContactNan Jiang

The First Affiliated Hospital, Sun Yat-sen University

jnan@mail.sysu.edu.cn+86 137 2540 7606

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026