Endometrial polyps
Conditions
Interventions
Experimental group:The levonorgestrel-releasingintrauterine system is placed immediately after the removal of endometrial polyps during hysteroscopic endometrial polypectomy(Manufacturer: Bayer Health
Control group:Histopathological examination of the tissue after surgery confirmed the presence of an endometrial polyp, and a left levonorgestrel-releasingintrauterine system was placed during the fir
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Premenopausal women aged > = 18 years old 2. Have a history of sexual activity 3. No childbearing requirements within 1 year 4. Ultrasound examination showed endometrial polyps 5. All were diagnosed as EP by hysteroscopy and pathological examination 6. There is an indication for TCRP, and TCRP is planned 7. Complete clinical data and complete follow-up 8. Whether the patient agrees to participate in this trial and has signed the informed consent form
Exclusion criteria
Exclusion criteria: 1. Pregnancy or lactation, menopause 2. Have a pregnancy plan within one year 3. There was no abnormality in biochemical examination, and there was no acute genital tract infection or other contraindications to transvaginal surgery 4. Combined with uterine fibroids, endometriosis, polycystic ovary syndrome and other gynecological benign and malignant diseases 5. Uterus is too large, malformed, etc 6. Combined with severe liver, kidney, heart and other organ insufficiency 7. Treatment of related drug allergies or surgical contraindications 8. Current or planned use of hormonal medications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Satisfaction of patients with LNG-IUS placement 12 months after TCRP surgery;Change of hemoglobin concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| The postoperative recurrence rates of endometrial polyps following 12-month postoperative follow-up;Bleeding patten;Menstrual change;Endometrial thickness;Expression of estrogen receptor in endometrium;Expression of progesterone receptor in endometrium;Inflammatory factors in uterine lavage fluid;The reverse effect of Mirena placement;The dropping rates of Mirena;The displacement rates for placing Mirena; | — |
Countries
China
Contacts
Public ContactZhi Zhifu
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed