Gynecological diseases
Conditions
Interventions
Magnesium sulfate group (Group M):A loading dose of 20 mg/ kg of 5% magnesium sulfate was added to 100 ml of isotonic saline for more than 10 min before induction of anesthesia. Intraoperative adminis
Control group (Group C):physiological saline will be used in place of the medication.
Sponsors
Sanming Second Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients who have undergone laparoscopic total hysterectomy, laparoscopic myomectomy, and laparoscopic removal of pelvic masses under general anesthesia; (2) Age: 18-65 years old; (3) Body Mass Index (BMI): 18-30kg/m2; (4) ASA grading: I to II; (5) Fully understand the test method and treatment purpose of this test, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) patients who are unable to cooperate, such as those with mental illness or intellectual disabilities; (2) Those with diabetes mellitus or thyroid gland abnormalities; (3) Long-term use of drugs that affect blood sugar metabolism (such as insulin, cortisol, etc.); (4) People with severe insufficiency of the heart, lungs, kidneys and other organs; (5) People who are allergic to magnesium sulphate; (6) a person who does not understand or rejects the test method; (7) Blood sugar before surgery is above normal range.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery -15;insulin resistance index; | — |
Secondary
| Measure | Time frame |
|---|---|
| General patient information;Pain rating;Initial blood glucose, blood glucose after 30 minutes of pneumoperitoneum, and blood glucose after surgery;The incidence of nausea and vomiting in patients within 24 hours after surgery;Blood magnesium concentration; | — |
Countries
China
Contacts
Public ContactYu Hong
Sanming Second Hospital
Outcome results
None listed