dysphagia
Conditions
Interventions
Swallowing training group:Swallowing training: Swallowing training includes basic training (pronunciation exercise training, cheek and throat training, tongue muscle training, ice stimulation), airway
100U injection group:100U salivary gland botulinum toxin injection combined with swallowing training therapy
200U injection group:200U salivary gland botulinum toxin injection combined with swallowing training therapy
Sponsors
Hebei Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: Select 120 patients with ischemic stroke who underwent tracheotomy in the neurology and rehabilitation medicine departments of Hebei Provincial People's Hospital First time. 1. stroke patients who meet the diagnostic criteria for ischemic stroke, aged 30-75 years, with a course of disease within 2 weeks to 6 months; 2.Patients undergoing tracheotomy; 3. Patients with swallowing disorders identified through Flexible Endoscopic Examination of Swallowing (FEES); 4. FEES endoscopic Murray secretion severity score >= 2 points; 5. Accompanied by salivation; 6. Voluntarily participate in this observation experiment, with approval and consent from the ethics committee, and sign the patient informed consent form ; 7.No obvious swallowing difficulties before onset.
Exclusion criteria
Exclusion criteria: 1. Patients with severe underlying diseases such as heart, liver, and kidney, as well as those with mental illnesses; 2. Having consciousness disorders, obvious cognitive and behavioral disorders, aphasia, etc., unable to cooperate in completing examinations and treatments; 3. Allergic to botulinum toxin type A; 4. The condition is unstable, accompanied by severe liver, kidney, and blood diseases, as well as gastroesophageal reflux disease, including fever, throat, and lung infections
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Drooling severity and frequency scales (DSFS);Murray Secretion Severity Scale;Wearing time of balloon tracheostomy tube;Unstimulated saliva flow rate (uSFR) ; | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical pulmonary infection score,CPIS; | — |
Countries
China
Contacts
Public ContactWang Xiaohan
Hebei Provincial People's Hospital
Outcome results
None listed