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Effects of non-steroidal anti-inflammatory drugs on the resorption of lumbar disc herniation: a protocol for a single-centre, randomized, double-blind, placebo-controlled study

Effects of non-steroidal anti-inflammatory drugs on the resorption of lumbar disc herniation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094586
Enrollment
Unknown
Registered
2024-12-25
Start date
2025-02-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar disc herniation

Interventions

Treatment group:Oral nonsteroidal anti-inflammatory drugs
Control group:Placebo taken orally

Sponsors

Suzhou hospital of traditional chinese medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Patients with lumbar disc herniation, aged 18 to 65 years; 2) the patient experienced moderate to severe pain (Visual Analogue Score [VAS] score>=4); 3) Not treated with non-steroidal anti-inflammatory drugs for at least one month prior to enrollment.

Exclusion criteria

Exclusion criteria: 1) Patients with a history of gastrointestinal bleeding or peptic ulcer; 2) Patients with contraindications to non-steroidal anti-inflammatory drugs, such as allergies or other conditions that make the use of non-steroidal contraindications unsafe; 3) Pregnant or lactating women; 4) Patients with severe comorbidities, such as severe cardiovascular or renal disease.

Design outcomes

Primary

MeasureTime frame
Reabsorption rate;—

Secondary

MeasureTime frame
Japanese orthopaedic association score, JOA score;Oswestry Disability Index, ODI;—

Countries

China

Contacts

Public ContactZhu Yu

Suzhou hospital of traditional chinese medicine

315361294@qq.com+86 188 9658 7582

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026