Dentin Hypersensitivity
Conditions
Interventions
Test group:Jun Xiao Bai Toothpaste Containing Mesoporous Nano-Hydroxyapatite with a Purity of 99%+
Control group:Baiyu Toothpaste
Sponsors
West China Hospital of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The whole body is in good health and can participate in the examination at any time during the trial; 2. Age between 18-65 years, both genders are acceptable; 3. Good compliance with check-ups during the trial period, able to follow health guidance, and capable of completing follow-up visits effectively; 4. At least 2 teeth with dentin hypersensitivity, with a Schiff Cold Air Sensitivity Score for cold air stimulation >=2; and a Visual Analogue Scale (VAS) score for cold air stimulation >=30 mm; 5. Women must not be in pregnancy or lactation; 6. No allergies to toothpaste or its ingredients; 7. No use of the following medications in the month before participating in the study: anticonvulsants, antihistamines, antidepressants, sedatives, anxiolytics; 8. Not currently using anti-dentin hypersensitivity toothpaste; not concurrently participating in other similar experimental studies; 9. Only people with continuous or more severe dentin hypersensitivity symptoms during the washout period are included as participants.
Exclusion criteria
Exclusion criteria: 1. The participant has acute pulpitis or apical periodontitis, oral mucosal chronic diseases such as lichen planus, leukoplakia, pemphigus, etc.; has chronic systemic diseases that cause intermittent or persistent pain, such as arthritis; or has a history of allergy to the test product; 2. The patient has received periodontal treatment (including periodontal surgery) within the past 6 months; 3. The mobility of sensitive teeth is greater than Grade I; sensitive teeth have moderate or deep caries, large fillings or crowns, obvious cracks in the enamel, or teeth with full crowns, abutment teeth for fixed or removable partial dentures; 4. The symptoms of dentin hypersensitivity are related to gum pain caused by occlusal trauma, heat, or chemical burns; diseases in other parts of the body are the cause of dentin hypersensitivity; 5. Has undergone dental treatment for tooth sensitivity in the past; teeth whitening within the past 8 weeks; use of over-the-counter professional anti-dentin hypersensitivity toothpaste within the past 3 months; 6. Has a history of needing long-term use of anti-inflammatory drugs, regular analgesics, anticonvulsants, antihistamines, antidepressants, sedatives, and other psychotropic medications; has diseases related to eating disorders and vomiting; 7. Women who are pregnant or breastfeeding; 8. Smokers; 9. Subjects deemed ineligible for enrollment by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Schiff Cold Air Sensitivity Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale for Pain;Side Effects; | — |
Countries
China
Contacts
Public ContactZhao Lei
West China Hospital of Stomatology Sichuan University
Outcome results
None listed