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Protective Effects of C5 Level Saline Injection Around the Phrenic Nerve in Interscalene Brachial Plexus Block

Protective Effects of C5 Level Saline Injection Around the Phrenic Nerve in Interscalene Brachial Plexus Block

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094577
Enrollment
Unknown
Registered
2024-12-25
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diaphragmatic paralysis

Interventions

Experimental group:Under ultrasound guidance, the location of C5 nerve roots was located, then the phrenic nerve was sought at the level of C5 and 10 ml of saline was injected around it to form a buff
Control group:Conventional interscalene brachial plexus block

Sponsors

Shanghai Jiao Tong University Af?liated Sixth People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients between the ages of 18 and 60 who need shoulder surgery. 2. Patients with American Society of Anesthesiologists (ASA) grade I-II, i.e., in good health or with mild systemic disease that does not affect mobility. 3. No history of respiratory diseases, especially no chronic obstructive pulmonary disease (COPD), asthma or other severe respiratory dysfunction. 4. No history of neurological disease, especially no known phrenic nerve injury or dysfunction. 5. Not pregnant, and no acute illness such as infection and fever before surgery. 6. Patients voluntarily participate in the study and sign an informed consent form to clearly understand the trial process and possible risks and benefits.

Exclusion criteria

Exclusion criteria: 1. Patients with prior chronic obstructive pulmonary disease (COPD), asthma or other respiratory diseases. 2. Patients with prior phrenic nerve injury, neurological diseases, or related dysfunction. 3. Patients with coagulation abnormalities or who are taking anticoagulant medications, as this may increase the risk of complications of nerve block. 4. Patients who are allergic to local anesthetic drugs or saline. 5. Pregnant or lactating female patients. 6. Patients who have previously received shoulder or neck nerve block anesthesia with complications. 7. Patients with severe cardiovascular disease or ASA grade III and above who may not be able to tolerate anesthesia or surgery. 8. Have acute infection, fever, skin breakage or other pathological conditions that may interfere with the operation and anesthesia effect.

Design outcomes

Primary

MeasureTime frame
The amplitude of diaphragm movement;Patient satisfaction;

Secondary

MeasureTime frame
Diaphragm thickness;Postoperative analgesic effect;Post-operative rate of respiratory complications;Degree of blood oxygen saturation;

Countries

China

Contacts

Public ContactZhao Jing

Shanghai Jiao Tong University Af?liated Sixth People’s Hospital

zhaojing@shsmu.edu.cn+86 189 3017 3656

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026