early pregnancy
Conditions
Interventions
Experimental group (Group A):Intravenous injection of remimazolam 0.3 mg/kg and alfentanil 10 µg/kg
Control group (Group B):Intravenous injection of remimazolam 0.3 mg/kg and fentanyl 1 µg/kg
Sponsors
Mianyang 404 Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1: Age range: 18-45 years old 2: Gestational age = 10 weeks 3: ASA rating ranges from Level I to Level II 4: BMI ranges from 18kg/m2 to 25 kg/m2 5: Voluntary acceptance of outpatient painless abortion procedure 6: Preoperative routine examinations of liver and kidney function, electrolytes, etc. showed no abnormalities
Exclusion criteria
Exclusion criteria: 1: Individuals who are allergic or have contraindications to opioid and benzodiazepine drugs 2: History of acute respiratory inflammation within two weeks without recovery 3: History of poor recovery from previous surgical anesthesia 4: electrolyte disturbance 5: Combination use of other types of sedatives and analgesics before surgery 6: Researchers believe that patients should not participate in this trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HR, MAP, SpO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Induction time of intravenous anesthesia;Wake-up time;VAS at awakening, VAS at 15 minutes of awakening, VAS at 30 minutes of awakening;Departure time from the hospital; | — |
Countries
China
Contacts
Public ContactZhang Weijie
Mianyang 404 Hospital
Outcome results
None listed