chronic neuropathic pain
Conditions
Interventions
Experimental group:Received 10 transcranial magnetic stimulation treatments within two weeks
Sponsors
Affiliated Hospital of Hangzhou Normal University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of peripheral nerve pathic pain in accordance with IASP, with a course of >=3 months; 2. Or neuropathic pain caused by nociceptive pain (ID PAIN scale>=2 points); 3. 18-75 years old; 4. The average daily pain VAS score in the past 1 week > 30 mm; 5. Can cooperate with clinical evaluation, magnetic resonance scanning and rTMS treatment; 6. No history of pain control medication adjustment within 1 week during the baseline assessment period; 7. Able to understand the nature and purpose of the study, willing to participate and able to comply with the requirements of the study protocol, and willing to cooperate with relevant follow-up.
Exclusion criteria
Exclusion criteria: 1. Contraindications to TMS and magnetic resonance examination (such as magnetic objects and implants or presence of metal pieces or foreign body residues in the body; presence of an acute wound or surgical wound that has not healed; claustrophobia; whether the vessel has any type of stent, clip or surgery; inability to lie on your back due to illness, etc.); 2. Patients with psychiatric illness, aphasia, or cognitive dysfunction (17 HAMDs>24, 14 HAMA>29, MMSE<=24); 3. Those with severe cardiopulmonary dysfunction, extreme weakness, unable to sit upright and cooperate with rehabilitation assessment and treatment; 4. Have other diseases that may interfere with the results of the study, such as epilepsy, myocardial infarction, etc.; 5. Pregnant or lactating women; 6. Is participating in other clinical studies or using other experimental drug treatments.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Neuropathic pain symptom and sign score;Pain interferes with daily activities;Sensory and emotional pain;Patient-rated overall pain improvement;Patient with changes in depression and anxiety;The overall health of the patient;Magnetic resonance functional connection; | — |
Primary
| Measure | Time frame |
|---|---|
| Pain intensity; | — |
Countries
China
Contacts
Public ContactXianwei Che
Affiliated Hospital of Hangzhou Normal University
Outcome results
None listed