Acquired superior oblique palsy is an acute unilateral or bilateral dysfunction of the superior oblique muscle caused by various acquired etiologies. Clinically, it is characterized by diplopia (including in primary gaze or reading position) and compensatory head posture.
Conditions
Interventions
Botulinum toxin injection treatment group:Injection Route: A conjunctival incision is made in the inferotemporal region near the vault of the globe for direct vision injection.
Control group:Neurotrophic medication therapy
Sponsors
The Zhongshan Ophthalmic Center,Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
12 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Patients with a definite diagnosis of acquired superior oblique palsy (if the etiology is clear and the primary condition is stable); 2.Age: 12 to 80 years; 3.Binocular diplopia; 4.Best corrected visual acuity of both eyes = 0.5; 5.Duration of illness < six months; 6.Vertical strabismus = 15 prism diopters (PD); 7.Voluntarily participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Horizontal strabismus =10 PD; 2.Coexisting other extraocular muscle palsies/orbital fractures; 3.History of strabismus or orbital surgeries; 4.History of myasthenia gravis; 5.Acupuncture treatment within one month prior to the therapy; 6.Congenital or decompensated congenital superior oblique palsy; 7.Pregnant women;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cure rate: Vertical strabismus in the primary gaze position = 2 PD, with the disappearance of binocular diplopia in the primary and reading positions.; | — |
Countries
China
Contacts
Public ContactJingchang Chen
The Zhongshan Ophthalmic Center,Sun Yat-sen University
Outcome results
None listed