None
Conditions
Interventions
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.BMI>=30kg/m^2; 2.General anesthesia, and operation time is expected to be more than 2 hours; 3.Age >=18 years; 4.ASA I-III; 5.Be clear about the research content before operation, participate voluntarily, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1.Morbid obesity (defined as BMI > 40kg/m^2); 2.Use of sleep AIDS, opioid analgesics, and psychotropic drugs within 1 month prior to the study; 3.Allergic to benzodiazepines and propofol; 4.Combined with myasthenia gravis; 5.Preoperative diagnosis of mental and psychological disorders; 6.Preoperative diagnosis of mental and psychological disorders;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Remazolam‘s ED95 and ED99 during bariatric surgery induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pharmacokinetic parameters of remazolam in obese population; | — |
Countries
China
Contacts
Public ContactQian Li
West China Hospital, Sichuan University
Outcome results
None listed