Nacrolepsy type 1
Conditions
Interventions
tVNS group:The stimulation of tVNS was located in the left auricular concha. The protocol has a pulse width of 500µs, a frequency of 25 hz, and an on/off period of 30 seconds. This stimulation lasted
stVNS group:The stimulation of tVNS was located in the left earlobe. The parameters are the same as tVNS. The protocol has a pulse width of 500µs, the frequency is 25 hz, and the on/off period is 30 s
Sponsors
Xijing Hospital, the First Affiliated Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
12 Years to 47 Years
Inclusion criteria
Inclusion criteria: (1)Age = 12 years old with the ability to understand and complete the self-reported questionnaires; (2)The patients met the international classification of sleep disorders third edition (ICSD-3) for NT1; (3)Local residence for more than 3 months; (4)Willingness to follow the trial plan as scheduled
Exclusion criteria
Exclusion criteria: (1)History of neurological disorders or other sleep disorders that may cause daytime sleepiness; (2)Severe psychiatric disorder involving a history of psychosis; (3)Any chronic condition affecting the ability to read or comprehend written instructions; (4)Any ear trauma; (5)Any substances abuse within the past 12 months; (6)Pregnant or nursing; (7)MRI contraindications; (8)Metallic implants or devices contraindicating tVNS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maintenance of Wakefulness test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Narcolepsy Severity Scale;Epworth Sleepiness Scale;14-item Hamilton Anxiety Rating Scale;17-item Hamilton Depression Rating Scale; | — |
Countries
China
Contacts
Public ContactLiuyonghong
Xijing Hospital, the First Affiliated Hospital of Air Force Military Medical University
Outcome results
None listed