chronic postsurgical pain
Conditions
Sponsors
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School
Eligibility
Sex/Gender
All
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Due to degenerative lumbar spondylolisthesis, degenerative lumbar spinal stenosis, lumbar disc herniation and other degenerative diseases of the lumbar spine, general anesthesia or two-level open transforaminal decompression of lumbar fusion and internal fixation were performed for the first time in Nanjing Gulou Hospital; (2) Age 45-65 years old, gender is not limited; (3) ASA grade I-III; (4) Subjects agree to participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Emergency surgery; (2) Acute fracture or infection; (3) Spinal tumors, spinal tuberculosis, lumbar scoliosis > 15°; (4) spinal surgery history; (5) the presence of central and peripheral nervous system, neuromuscular system diseases (polio, peripheral neuropathy, etc.) and equipped with a pacemaker; (6) serious organ dysfunction of heart, brain, liver, kidney, etc.; (7) persons addicted to alcohol or drugs; (8) preoperative history of chronic pain and long-term use of analgesic and/or sedative drugs; (9) Preoperative resting pain score (NRS score) > 3; Body mass index (BMI) > 35; (11) Communication or cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chronic pain incidence and pain score 90 days after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and severity of acute postoperative pain;Anxiety, depression and sleep at 90 days after surgery;Types and dosage of analgesics used during and after operation;Postoperative complications during hospitalization;Time of first landing after surgery;Preoperative sleep score;Score of preoperative anxiety and depression;Anxiety and depression score at 24h and 48h after operation;Pain situation, nature of pain, type and dose of remedial analgesics used 90 days after operation;Pain situation, nature of pain, type and dose of remedial analgesics used 30 days after operation;Blood gas indexes during and after operation; Postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactMa Zhengliang
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School
Outcome results
None listed