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A randomized, open, blank controlled, multicenter clinical study of radiation-induced skin injury in head and neck cancer patients treated with medical radiation protectant spray

A randomized, open, blank controlled, multicenter clinical study of radiation-induced skin injury in head and neck cancer patients treated with medical radiation protectant spray

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094489
Enrollment
Unknown
Registered
2024-12-24
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer

Interventions

Control group:Only basic skin care is given after the start of radiotherapy. When grade III and above radiation skin damage occurs, anti-infection and anti-inflammatory therapy is given
Experimental group:After the beginning of radiotherapy, basic skin care and medical radiation protection spray were given to intervene, spraying evenly on the skin or mucous membrane in the irradiatio

Sponsors

Department of Radiotherapy, the First Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Age 18-80; 2) Patients with head and neck tumors undergoing radiotherapy (confirmed by histopathology and/or cytology); 3) The physical status scores of ECOG were 0,1,2 and 3; 4) No serious medical skin diseases (especially radiation field skin diseases, systemic lupus erythematosus); 5) Signed written informed consent; 6) The subjects are able to read, understand, follow the study procedures and independently complete the work required for the study

Exclusion criteria

Exclusion criteria: 1) The subjects have mental illness and severe cognitive impairment; 2) The investigator believes that the administration of the study treatment may obfuscate the study results or create an uncertain risk; 3) Patients who refused follow-up; 4) Participate in another clinical trial investigating a drug or medical device; 5) Patients who are allergic to related drugs.

Design outcomes

Primary

MeasureTime frame
Incidence and classification of radiation-induced skin injury;

Secondary

MeasureTime frame
radiation-induced skin injury relief/healing time;Quality of life score;Pain score;Physical condition score;Psychological status score;Pruritus score;

Countries

China

Contacts

Public ContactXin Jiang

The First Hospital of Jilin University

jiangx@jlu.edu.cn+86 158 0430 2750

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026