Hip fracture
Conditions
Interventions
Experimental Group:In the experimental group, bupivacaine liposome injection was used for local infiltration analgesia before the surgical wound was closed, and the specific method was to infiltrate t
Control group:None
Sponsors
Shanghai Sixth People's Hospital Affiliated to Shanghai JiaoTong University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age> = 65 years old, gender is not limited. 2. Diagnosed with hip fracture (including femoral neck, intertrochanteric or subtrochanteric fracture) and planned to undergo surgery within 48 hours of diagnosis. 3. The American Society of Anesthesiologists (ASA) grading standard is I.~III. 4. Subjects have a detailed understanding of the nature, significance and potential risks of the trial, and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Cognitive and communication disorders. 2. Unable to walk normally before the fracture. 3. Patients with multiple injuries or severe heart block and unstable coronary heart disease. 4. Presence of severe liver or renal system disease. 5. Patients with coagulation dysfunction or who have not stopped anticoagulants before surgery. 6. Patients with a history of opioid or amide local anesthetic allergy. 7. Subjects who have participated in other clinical trials within 3 months prior to randomization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients who were ambulatory from the end of surgery to 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients who were able to get out of bed within 48 hours and 72 hours after surgery;Opioid consumption at 24 hours, 48 hours, and 72 hours after surgery;Pain intensity scores (NRS) at 24 hours, 48 hours and 72 hours after surgery; | — |
Countries
China
Contacts
Public ContactWeitao Jia
Shanghai Sixth People's Hospital Affiliated to Shanghai JiaoTong University
Outcome results
None listed