Aspiration pneumonia
Conditions
Interventions
Control group:
NA
Sponsors
Zhejiang Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1). Patients aged 18 years and above.; (2). Patients diagnosed with sialorrhea; (3). Patients with no pulmonary infection in the past 2 weeks; (4). Patients voluntarily participate in the study and provide informed consent.
Exclusion criteria
Exclusion criteria: (1). History of parotid gland disease (e.g., mumps); (2). History of neuromuscular disease (e.g., myasthenia gravis, Lambert-Eaton myasthenic syndrome); (3). Patients currently taking anticholinergic drugs; (4). Pregnant or breastfeeding women, or individuals known to be allergic to BoNT-A; (5). Patients currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of aspiration pneumonia in 3 months; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of aspiration pneumonia episodes in 3 months;The time to the first occurrence of aspiration pneumonia;Unstimulated salivary flow rate;Drooling Severity and Frequency Scale (DSFS) score; | — |
Countries
China
Contacts
Public ContactHuihua Hong
Zhejiang Provincial Hospital of Chinese Medicine
Outcome results
None listed