Hypospadias
Conditions
Interventions
Experimental group:Inject SVF-gel
Control group:None
Sponsors
Shenshan Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The age of the patient on the day of signing the informed consent form is more than 6 months; 2. Diagnosis of congenital hypospadias; 3. No surgical treatment; 4. Patients who need to reconstruct the urethra with a leather tube to evaluate the surgical plan; 5. Those whose vital signs are stable and can tolerate surgery after routine examination; 6. Patients who are in good mental state, able to follow the doctor's instructions, and have regular follow-up visits; 7. The patient or legal guardian understands and is willing to participate in this clinical trial and provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Pre-existing diseases that will affect the healing of the reconstituted urethra (such as malignant tumors, autoimmune diseases); 2. Patients are immunosuppressed during the screening period due to underlying disease, long-term immunosuppressant therapy, or use of high-dose glucocorticoids (i.e., receiving = 40 mg of prednisone or the equivalent of prednisone daily for = 2 weeks); 3. Difficult-to-control hyperglycemia (e.g., HbA1c >12.0%); 4. Those with serious uncontrolled diseases or acute infections in the whole body and other serious organ diseases such as heart, lung and encephalopathy; 5. Patients with mental illness; 6. Those who are considered inappropriate by the researchers; 7. Patient has participated in this study at any time in the past.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of urinary fistula; | — |
Countries
China
Contacts
Public ContactXiaolian Xiao
Shenshan Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed