None
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Have experienced more than 12 hours of fasting within at least the past year and do not cause hypoglycemia; 2. 18<=age<=65; 3. 18.5<=BMI; 4. Gender is not limited; 5. Agree to sign the informed consent form; 6. Agree to provide blood, feces, saliva, hair and urine according to the experimental design, and agree to fill in the questionnaire independently or cooperate with the questionnaire.
Exclusion criteria
Exclusion criteria: 1.History of hypoglycemia; 2.The fasting blood glucose value of the enrollment should not be lower than or beyond the normal range [3.9~6.1 mmol/L]; 3.Medication (including hypoglycemic drugs such as insulin and metformin, etc.); 4.Alcohol consumption one month before and during the experiment; 5.Take antibiotics at least 1 month before the experiment; 6.Smokers and coffee drinkers before and during the experiment; 7.Common chronic diseases such as diabetes, hypertension; 8.autoimmune diseases; Medical diseases include the mucous membranes of the digestive tract, lungs, heart, vasculature, liver, and kidneys; 9.Eating disorders (e.g. anorexia due to stress or anxiety) and abnormal eating habits (e.g. overeating and overeating at night); 10.Have any mental illness; 11.Severe hair loss and absence of hair; 12.Participation in other medical studies or fasting research projects; 12-hour fasting experience within 2 months prior to enrollment; 13.Pregnant and lactating women; 14.Subjects who have a clear travel plan during the experiment and are unable to provide a sample;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glutamyl transferase;Aspartate aminotransferase; Alanine aminotransferase;Total cholesterol;High-density lipoprotein;Low-density lipoprotein;Triglycerides;Glycosylated hemoglobin;Insulin;Blood sugar; | — |
Countries
China
Contacts
First Affiliated Hospital of Kunming Medical University