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Effect analysis of cervical cerclage on preventing preterm birth and formulation of standardized management of cervical incompetence

Effect analysis of cervical cerclage on preventing preterm birth and formulation of standardized management of cervical incompetence

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094467
Enrollment
Unknown
Registered
2024-12-23
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical incompetence

Interventions

Cervical cerclage group:Cervical cerclage
Cervical cerclage and vaginal progesterone group:The application of vaginal progesterone after cervical cerclage

Sponsors

Obstetrics and Gynecology Hospital of Fudan university
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Pregnant women who choose to give birth in the Obstetrics and Gynecology Hospital of Fudan University from January 1, 2015 to December 31, 2024 meet the following conditions: 1. Singleton pregnancy; 2. Conform to the diagnosis of cervical insufficiency (modified by 2014 ACOG definition); 3. Prenatal check-up and delivery in our hospital; 4. Fetal survival in utero.

Exclusion criteria

Exclusion criteria: 1. 2 or more multiple pregnancies; 2. Fetal malformations; 3. Uterine malformations; 4. Patient refuses follow-up tocolytic treatment; 5. Lost to follow-up cases such as not giving birth in this hospital, incomplete clinical data or missing pregnancy outcomes; 6. Age< 18 years; 7. Therapeutic preterm birth.

Design outcomes

Primary

MeasureTime frame
Incidence of delivery at less than 37 week;

Secondary

MeasureTime frame
Incidence of delivery at less than 26 week;Incidence of delivery at less than 34 week;Composite adverse neonatal outcomes;

Countries

China

Contacts

Public ContactHaiyan Liu

Obstetrics and Gynecology Hospital of Fudan university

luohuahutong@163.com+86 21 3318 9900

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026