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the effectiveness of continuous Compression-synchronous ventilation (Bio-CPR)

Study on the effectiveness of continuous compression-synchronous ventilation (Bio-CPR) in the ACLS stage of cardiopulmonary resuscitation (ACLS) based on the bionic concept to explore the best mechanical ventilation strategy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094466
Enrollment
Unknown
Registered
2024-12-23
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Witnessed cardiac arrest

Interventions

Bio-CPR experimental group:Bio-CPR ventilation mode
Traditional compression/ventilation mode group:Traditional compression/ventilation mode

Sponsors

Guangdong Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. 18-65 years old; 2. Cardiac arrest with witnesses; 3. Onset - compression start time<5 minutes; 4. Initial ventricular fibrillation rhythm; 5. Endotracheal intubation and use of a mechanical chest CPR device; Patients with OHCA who meet the above conditions

Exclusion criteria

Exclusion criteria: 1. OHCA patients who are not suitable for mechanical compression ventilation; 2. The participant or his/her legally authorized representative (LAR) is unable or unwilling to provide written informed consent.

Design outcomes

Primary

MeasureTime frame
Mean tidal volume;—

Secondary

MeasureTime frame
Mean minute ventilation and end-tidal carbon dioxide;—

Countries

China

Contacts

Public ContactXin Li

Guangdong Provincial People's Hospital

xlidoct@qq.com+86 20 37637426

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026