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Relationship between Carotid Intraplaque Neovascularization and Immune-inflammatory Biomarkers with Coronary Stenosis

Relationship between Carotid Intraplaque Neovascularization and Immune-inflammatory Biomarkers with Coronary Stenosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094458
Enrollment
Unknown
Registered
2024-12-23
Start date
2023-12-18
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Stenosis

Interventions

Index test:Correlation of intraplaque neovascularization in carotid arteries with systemic immune-inflammatory response index, systemic inflammatory response index, systemic immune-inflammatory index,

Sponsors

the Second People's Hospital of Hefei
Lead Sponsor

Eligibility

Sex/Gender
All
Age
37 Years to 87 Years

Inclusion criteria

Inclusion criteria: (1) age=18 years; (2) clinical indication for CAG to assess CAD, with confirmed coronary artery lesions by CAG; (3) no clinical contraindications for CAG; (4) local carotid intima-media thickness (IMT) =1.5mm.

Exclusion criteria

Exclusion criteria: (1) history of carotid endarterectomy or percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG); (2) presence of diseases associated with thickening of the carotid intima-media (such as immune diseases, arteritis, etc.);(3) presence of other cardiac diseases (such as valvular heart disease, myocarditis, dilated cardiomyopathy, hypertrophic cardiomyopathy, known or suspected cardiac shunts, etc.); (4) severe hepatic or renal insufficiency, systemic infectious diseases, or coagulation disorders; (5) incomplete clinical data; (6) poor quality of carotid ultrasound images

Design outcomes

Primary

MeasureTime frame
Carotid intraplaque neovascularization score;Plaque’s thickness;Degree of coronary artery stenosis;number of coronary artery lesions;Gensini score;Systemic immune inflammation response index;Systemic inflammatory response Index;systemic immune inflammation index;Neutrophil to lymphocyte ratio;platelet to lymphocyte ratio;Monocyte to lymphocyte ratio;Neutrophil to HDL-C ratio;Sensitivity;Specificity;Accuracy;

Secondary

MeasureTime frame
Carotid IMT;Plaque’s length;Plaque’s echo;

Countries

China

Contacts

Public ContactYue, Wu

the Second People's Hospital of Hefei

a17839433705@163.com+86 178 3943 3705

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026