Cerebral small vessel disease with nonspecific symptoms such as dizziness and headache
Conditions
Interventions
According to the SCD-Q9 questionnaire, those who score = 5 are classified as SCD group, while those who score < 5 are classified as CN group:NA
Sponsors
The affiliated hospital of southwest medical university
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for CSVD in the Chinese Expert Consensus on the Diagnosis and Treatment of Cerebral Small Vessel Disease 2021; 2. Has normal baseline cognition (normal MOCA, MMSE); 3. Voluntary participation in this study;
Exclusion criteria
Exclusion criteria: 1. The presence of a clear previous history of other cerebrovascular disease, traumatic brain injury, or CO poisoning; 2. Presence of other disorders affecting cognitive function (Parkinson's disease, dementia, epilepsy, encephalitis, brain tumors, etc.); 3. Severe mental illnesses (schizophrenia, bi-directional affective disorder, severe depression, severe anxiety, etc.); 4. Severe metabolic diseases, severe heart, lung, liver and kidney diseases; 5. Those who are unable to participate in the assessment due to severe visual, hearing or motor impairments. 6. Incomplete clinical information or inability to perform MRI;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SCD-Q9;Montreal Cognitive Assessment, MoCA;Mini-Mental State Examination;stroop; | — |
Secondary
| Measure | Time frame |
|---|---|
| alkaline phosphatase;creatinine;cholesterol;uric acid;homocysteine (Cys);MAES;Pittsburgh Sleep Quality Index, PQSI;Hamilton Anxiety Scale, HAMA;Hamilton Depression Scale, HAMD; | — |
Countries
China
Contacts
Public ContactTan Hua
The affiliated hospital of southwest medical university
Outcome results
None listed