Gingival recession with infra-bony defects
Conditions
Interventions
Test Group:Connective Tissue Wall Technique: Make papilla preservation incisions and a semi-thickness to full-thickness flap. Then fully debride granulation tissue and expose the infra-bony defect tho
Control Group:Combined GTR and bone subsititutes grafting: After thorough debridement and complete exposure of the infra-bony defect, fill the DBBM (Geistlich Bio-oss) subsititutes. Suture the outer f
Sponsors
Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Age 18-70 years old, female or male. 2) Patients already accepted initial periodontal treatment. 3) Patients with at least one tooth classified by the Cairo classification as RT2/RT3 gingival recession without tooth mobility and CBCT showing a infra-bony defect of at least 3mm without bleeding on probing and a probing depth of no more than 3mm at adjecent teeth. 4) No smoking or less than 10 cigarettes per day; 5) No medical contraindications for oral surgery or regenerative surgery.
Exclusion criteria
Exclusion criteria: 1) Patients with a history of open debridement surgery at the infra-bony defect site within the past one year; 2) Patients without RT2/RT3 gingival recession or infra-bony defect site. 3) Patients with advanced perodontitis. 4) Patients with uncontrolled dabetes, ie, fasting plasma glucose >=8.88mmol/L after medication control; 5) Patients with uncontrolled severe hypertension, ie, >160/90 mmHg; 6) Patients with cardiovascular disease, ie, class II or higher cardiac function disorder; 7) Patients with impaired liver or renal function, ie, serum creatinine > 1.5 mg/dl or with active hepatitis or decompensated cirrhosis; 8) Patients with a history of full-dose radiation therapy or local radiation therapy in the head and neck area; 9) Patients with impaired immune function; 10) Patients who smoke tobacco or tobacco equivalents or chew tobacco, >= 10 cigarettes daily; 11) Patients with poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gingival Recession,REC;Filled infra-bony Rate, FBR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pocket Probing Depth, PPD;Keratinized Gingival Width, KGW;Bleeding Score Index, BI;Plaque Index, PI;Gingival Area Gain, GAG;Gingival Mean Thickness, GMT;Tissue Thick Change, TTC; | — |
Countries
China
Contacts
Public ContactNi Jing
Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed