Gastrointestinal environment disorders, mucosal barrier disorders and related diseases
Conditions
Interventions
PVB group:Unilateral paravertebral nerve block at four points (0.375% ropivacaine, 15ml at each point) was received 30min before surgery
Control group:No block operation was performed before surgery, and other operations were the same as those in PVB group
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Patients aged 18-65 years who plan to undergo elective open hepatectomy; 2) American College of Anesthesiologists (ASA) Levels I to III; 3) AGI grade 0 before operation, with no gastrointestinal related underlying diseases; 4) Sign informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1) 65 years old; 2) Contrainidators for paravertebral block treatment: skin infection or ulceration on the body surface of the back, spinal or thoracic deformity, spinal cord injury above the T10 level, allergy to amide local anesthetics, etc; 3) Significant abnormal coagulation function: platelet count 65s; 4) any neurological or mental illness, including a history of substance abuse, anxiety or depression, or treatment; 5) Special personnel, such as pregnant women, brain death patients; 6) The patient plans to undergo additional gastrointestinal surgery; 7) Unable to cooperate with the study for any reason, such as difficulty in language understanding, refusal to participate in the study, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement rate of postoperative gastrointestinal function score ; | — |
Secondary
| Measure | Time frame |
|---|---|
| ntestinal fatty acid binding protein(I-FABP);Visual Analogue Scale(VAS) ; | — |
Countries
China
Contacts
Public ContactDanfeng Wang
Fujian Provincial Hospital
Outcome results
None listed