Application of target guided liquid therapy guided by transesophageal echocardiography in thoracoscopic radical resection of lung cancer

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400094413

Enrollment

Unknown

Registered

2024-12-23

Start date

2024-12-23

Completion date

Unknown

Last updated

2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Conventional liquid therapy group:conventional fluid therapy

Target oriented liquid therapy group:Targeted liquid therapy guided by dynamic monitoring of ? SV using TEE

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age>18 years old; 2. ASA grades I-III; 3. BMI 15~30 kg/m^2.

Exclusion criteria

Exclusion criteria: 1. Individuals with contraindications for TEE; 2. Individuals with severe cardiovascular, brain, lung, liver, and kidney diseases; 3. Surgical duration<1 hour; 4. Refuse to participate in this trial.

Design outcomes

Primary

Measure	Time frame
Postoperative Recovery Quality Score;	—

Secondary

Measure	Time frame
Arterial blood lactate, aLac;Centrol venous-to-arterial carbon dioxided tension difference, Pcv-aCO2;Centrol venous oxygen saturation, ScvO2;Oxygen delivery index, DO2I;heart rate;blood pressure;Incidence of postoperative cognitive impairment;VAS scores;Postoperative complications;Inflammatory factor levels;Infusion volume;Liquid output;Number of cases of vasoactive drug use;Pull out time;PACU stay time;First exhaust time after surgery;Removal time of drainage tube;Postoperative hospitalization days;	—

Measure

Time frame

Arterial blood lactate, aLac;Centrol venous-to-arterial carbon dioxided tension difference, Pcv-aCO2;Centrol venous oxygen saturation, ScvO2;Oxygen delivery index, DO2I;heart rate;blood pressure;Incidence of postoperative cognitive impairment;VAS scores;Postoperative complications;Inflammatory factor levels;Infusion volume;Liquid output;Number of cases of vasoactive drug use;Pull out time;PACU stay time;First exhaust time after surgery;Removal time of drainage tube;Postoperative hospitalization days;

—

Countries

China

Contacts

Public ContactMeng Xiangdi

Xuzhou Central Hospital

704320691@qq.com+86 153 6588 8933

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026