Depressive symptoms
Conditions
Interventions
Active tACS+EFWMT:Combining tACS and Emotional Face Working Memory Training
Sham tACS + EFWMT:Combining sham tACS and Emotional Face Working Memory training
Sham tACS+NFWMT:Combining sham tACS and Neutral Face Working Memory Training
Sponsors
Institute for Brain Research and Rehabilitation
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Meeting the criteria of DSM-5 for major depressive disorder (MDD), at least one depressive episode after 50 years old; 2.A total score >=12 on Montgomery-Asberg Depression Rating Scale (MADRS); 3.Above 50 years old; 4.Right handness; 5.Agreed to participate in this study and signed an informed consent form;
Exclusion criteria
Exclusion criteria: 1.A history of severe suicidal or self-injurious behavior; 2.Diagnosed with mental illness other than Depression disorder, Anxiety disorder, Sleep disorder and Somatoform disorder, or accompanied by psychotic symptoms; 3.A history of neurodegenerative diseases, such as Alzheimer's disease, Parkinson disease; 4.A combination of serious physical, infectious, or immune system disorders, such as Coronary heart disease, Multiple Sclerosis; 5.A history of organic brain disease, history of external brain injury, or history of surgery; 6.Persons with drug dependence or alcohol dependence within one year; 7.History of previous seizures;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive function;Sleep status;Safety;Selt-reported psychological assessments; | — |
Countries
China
Contacts
Public ContactLijuan Huo
Institute of Brain Science and Rehabilitation Medicine, South China Normal University
Outcome results
None listed