Painless gastroscope for elderly patients
Conditions
Interventions
one group:Increase or decrease the dose of remazolam by a gradient
Sponsors
Hainan General Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) gender is not limited, the patient's age is 65~80 years old, body mass index (BMI) 18~26kg/m2, American Society of Anesthesiologists (ASA) classification I~II; 2) New York Heart Association (NYHA) cardiac function classification ?~II; 3) gastroscopy time is not more than 15min; 4) the patient's sanity is clear, and he or she clearly understands and voluntarily participates in the study, and voluntarily signs the informed consent form to cooperate with the experimental test.
Exclusion criteria
Exclusion criteria: (1) patients requiring complex endoscopic techniques for diagnosis and treatment; (2) those with intention of endotracheal intubation; (3) those with difficulty in respiratory management; (4) patients with a diagnosis of grade 3 or higher hypertension who do not have satisfactory blood pressure control with antihypertensive medications; (5) patients with severe heart, brain, lung, liver, kidney, Parkinson's disease, diabetes mellitus, and other disorders; (6) chronic opioid users or history of psychotropic medication use; (7) Patients with preoperative cognitive dysfunction; (8) those with a seated systolic blood pressure of less than 90 mmHg during screening; (9) those who are allergic to or have contraindications to benzodiazepines, opioids, propofol, or lidocaine; and (10) those who have participated in a clinical trial of another drug within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether the patient experienced choking or somatic reaction during gastroscope placement via the pharynx; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate,HR;Blood pressure,BP;saturation of pulse oxygen,SPO2;bispectral index, BIS;modified observer's assessment of awareness/sedation,MOAA/S; | — |
Countries
China
Contacts
Public ContactWang Lin
Hainan General Hospital
Outcome results
None listed