Colorectal cancer
Conditions
Interventions
Lidocaine group (Group L) :Method of lidocaine administration in group L: Lidocaine was given with a load of 1.0mg/kg within 15min before induction of general anesthesia, and intravenous pump was inje
control group (Group C):Control group administration method: Saline was given in the same way as above.
Sponsors
The First Affiliated Hospital of Shanxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective radical resection of colorectal cancer; 2. ASA classification :?-? level; 3. age: 18-80 years old; 4. body mass index (BMI) : 18.5-28 kg/m^2; 5. Preoperative Christensen score <= 4 points; 6. The patient agrees to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. known allergy to lidocaine and other amide anesthetics; 2. Patients with severe cardiovascular system diseases; 3. patients with abnormal liver and kidney function; 4. patients with cerebrovascular disease; 5. Patients with mental diseases; 6. History of chronic pain; 7. Preoperative neuromusculoskeletal disease; 8. Patients with severe malnutrition before surgery; 9. preoperative internal environment disorders (such as hypokalemia); 10. complicated with other malignant tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative fatigue syndrome positive rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative fatigue syndrome score;visual analogue scale(VAS);Pittsburgh sleep quality index(PSQI);Quality of Recovery Scale-15(QoR-15);The dosage of postoperative analgesic drugs;Length of stay;Total hospital expenditure;Time of first postoperative movement;First postoperative exhaust time;Time of first postoperative defecation; | — |
Countries
China
Contacts
Public ContactZhang Wenjie
The First Affiliated Hospital of Shanxi Medical University
Outcome results
None listed