Rheumatoid arthritis
Conditions
Interventions
Case group:csDMARDs+L-Tryptophan dietary supplement
Sponsors
Dazhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. All met the diagnostic criteria for RA revised by the American College of Rheumatology in 2010; 2. RA patients aged >=18 years and =3.0; 3. Patients who have been treated with at least one type of csDMARDS (including methotrexate, hydroxychloroquine sulfate, leflunomide, iratimod, etc.) before enrollment; 4. Patients who have good compliance, signed the informed consent form, and are able to complete the trial according to the protocol.
Exclusion criteria
Exclusion criteria: 1. Patients treated with biologics; 2. Patients with malignant diseases such as peptic ulcer, blood system diseases, mental disorders and tumors; 3. Those with previous or current medical history with inflammatory joint diseases other than rheumatoid arthritis, or those with other systemic autoimmune diseases; 4. Those with a recent history of major surgery or trauma; 5. Patients with poorly controlled concomitant diseases that are considered clinically significant by the investigator to be severe; 6. Those who have poor compliance and cannot cooperate with the completion of the test; 7. Those who have a history of depressive disorders and are taking related medications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease activity score (DAS28);Swollen joint count (SJC28);Tender joint counts (TJC28);Erythrocyte sedimentation rate (ESR);C-reactive protein (CRP);Rheumatoid factor (RF); | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analog Scal Score;Health Assessment Questionnaire for the Disability Index; | — |
Countries
China
Contacts
Public ContactFanxin Zeng
Dazhou Central Hospital
Outcome results
None listed