Non-cardiac diseases
Conditions
Interventions
Observation group:None
Sponsors
The Second Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1)Patients expected to undergo elective non-cardiac surgery under general anesthesia with endotracheal intubation; (2)Age >= 18 years; (3)ASA grade I~III; (4)Voluntary participation in this clinical trial with signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Have a history of neurological or psychiatric illness or recent use of drugs affecting the central nervous system; (2) Patients with preoperative cognitive dysfunction determined by MMSE scale; (3) Those with severe impairment of auditory, visual and language system functions; (4) Those with severe impairment of heart, lung, kidney and liver function; (5) Identifying/suspected of abusing or long-term use of narcotic sedative analgesics; (6) Those who are allergic to conventional anesthetic drugs or have contraindications; (7) Body weight less than 70% or more than 130% of ideal body weight; (8) Postoperative coma or epilepsy; (9) Patients with difficult airways requiring awake intubation or who have been diagnosed with moderate to severe OSAS; (10) Those who are abstaining from alcohol; (11) Those who participated in other clinical studies during the same period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between Electroencephalography parameters and sedation depth of remimazolam; | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation and consistency between anesthesia depth index(Ai) and bispectral index(BIS);Correlation Between Anesthesia depth index (Ai), Bispectral Index (BIS), and End-Tidal Carbon Dioxide Levels Under Total Intravenous Anesthesia with Remimazolam; | — |
Countries
China
Contacts
Public ContactLi Hong
The Second Affiliated Hospital of Army Medical University
Outcome results
None listed