Cardia valve disease
Conditions
Interventions
Bupivacaine hydrochloride group (Group B):Erector spinal plane block
Liposomal bupivacaine group (Group L):Erector spinal plane block
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing minimally invasive cardiac valve surgery with elective cardiopulmonary bypass via intercostal incision 2. No gender limitation, age between 18 and 80 years old 3. ASA classification I-III 4. EuroScore <5 5. Body mass index (BMI) <31 kg/m^2 6. Understand and administer the Postoperative Intravenous Analgesia Pump (PCIA) independently or with assistance
Exclusion criteria
Exclusion criteria: 1. Refuse to participate or unable to communicate 2. Participating in other clinical trials 3. Contraindications of nerve block, including infection at puncture site, severe coagulopathy and severe spinal deformity 4. Patients with neurocognitive impairment (NCD), depression and other mental diseases before surgery, or unable to complete the postoperative scale 5. Patients or accompanying family members were serious anxious before surgery 6. Long-term use of analgesics, or known abuse of alcohol, drugs or narcotic drugs 7. Accompanied by other conditions, such as breastfeeding, pregnancy, tumor, severe disability, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient satisfaction;VAS scores at rest and cough;The first PCIA blous time;PCIA blous times;breakthrough pain;Postoperative remedial analgesia;Postoperative nausea and vomiting, skin itching, delirium;Mechanical ventilation time;Postoperative death and major complications;Chronic pain; | — |
Countries
China
Contacts
Public ContactKefang Guo
Zhongshan Hospital, Fudan University
Outcome results
None listed