Disorders of consciousness
Conditions
Interventions
Consciousness impairment group:None
Healthy control group:None
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Consciousness impairment group: 1. DOC caused by various brain injury diseases that meet the diagnostic criteria for vegetative state (loss of cognitive ability, no conscious activity, inability to execute commands, ability to open eyes automatically or under stimulation, sleep-wake cycle, inability to comprehend and express language, maintenance of basic vital signs such as respiration, blood pressure, etc., and preservation of basic functions of the subthalamus and the brainstem) and diagnostic criteria for minimally conscious state (executing simple commands, making gestures or responding whether accurately or not, understanding and expressing language, and responding to actions and emotions appropriate to the external environment); patients who Patients with the diagnostic criteria of minimal consciousness (can understand and express language and respond to the external environment by making simple commands, gestures, or yes/no answers, regardless of whether they are accurate or inaccurate, and can respond to the external environment with appropriate actions and emotions); 2.This is the first episode of the disease; 3. Age >= 18 years; 4.Have not used drugs that affect gastrointestinal motility 3 days before the trial; 5.Agreed to sign the informed consent form for this clinical study. Healthy control group: 1. Physically and mentally healthy, without chronic diseases; 2. Age >= 18 years old.
Exclusion criteria
Exclusion criteria: Consciousness impairment group: 1. Combined gastrointestinal obstruction, bleeding, gastrointestinal surgery, malignant tumours and other severe gastrointestinal impairment; 2. Pregnant women and patients after caesarean section; 3. People with severe organ dysfunction; 4. Combined with severe abdominal distension, obesity, abdominal wall deformities and other inability to perform abdominal ultrasonography; 5. Patients with incomplete medical records, who are unable to carry out data collection. Healthy control group: 1.Within one week, there are digestive symptoms such as nausea, vomiting, acid reflux, etc; 2. Those who have taken medication or health supplements within one month; 3. Pregnant women and cesarean section, the latter; 4. Individuals with gastrointestinal diseases or a history of surgery or abdominal surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastric emptying rate ;Motility index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nutritional status;Complication;Risk of aspiration; | — |
Countries
China
Contacts
Public ContactWang Yulong
Shenzhen Second People's Hospital
Outcome results
None listed