Breast cancer
Conditions
Interventions
Flap Thickness >= 5 mm Group:None
Flap Thickness <5 mm Group:None
Sponsors
Affiliated hangzhou first people's hospital, zhejiang university school of medicine
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Aged 18 years or older; 2.Female; 3.Preoperative pathology confirmed invasive breast cancer or ductal carcinoma in situ (DCIS); 4.Clinical T1 or T2 (maximum tumor diameter <=5 cm); 5.Clinically negative axillary lymph nodes (ALN) (clinical physical examination and ultrasound suggest negative axillary lymph nodes; patients with suspicious axillary lymph nodes must have negative fine-needle aspiration cytology results); 6.Negative sentinel lymph nodes intraoperatively; 7.No clinical or imaging evidence of distant metastasis; 8.Implant volume less than 500cc; 9.18<BMI<35; 10.Intraoperatively, the surgeon assesses the flap as having good blood supply and plans to proceed with prepectoral breast reconstruction (PBR); 11.Able and willing to sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1.History of breast radiotherapy or patients requiring postoperative radiotherapy; 2.Patients requiring two-stage breast reconstruction; 3.Patients undergoing skin-sparing mastectomy (SSM); 4.Patients with significant breast ptosis requiring Wise-pattern or other breast-lifting techniques for subcutaneous mastectomy; 5.Patients receiving immediate or delayed contralateral breast symmetry surgery; 6.History of breast cancer (e.g., recurrence after breast-conserving surgery on the same side); 7.Pregnant or lactating women; 8.Patients with comorbidities such as diabetes or connective tissue diseases; 9.Long-term active smokers; 10.BMI>=35;BMI<=18; 11.Patients whose flap conditions are deemed unsuitable for PBR surgery by the surgeon;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Aesthetic outcomes;Patient satisfaction; | — |
Countries
China
Contacts
Public ContactJian Liu
Affiliated hangzhou first people's hospital, zhejiang university school of medicine
Outcome results
None listed