Osteoarthritis
Conditions
Interventions
Experimental group:Ketoprofen Cataplasms
Control group:Flurbiprofen gel plaster
Sponsors
Affiliated Zhongshan Hospital of Dalian University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: (1)Patients agree to participate in this study and sign a written informed consent form; (2)Aged 18~75 years old; (3)Grade I-III knee OA (according to clinical diagnostic criteria); (4)Without the history of bleeding,asthma,severe heart\hepatic\renal insufficiency, non-steroida allergy, etc.; (5)The drugs used in experimental group and control group are contained in the drug list specified in this study.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: (1)Previous treatment that may affect the drugs efficacy; (2)With open wounds, scars, or ulcers in the area where the Cataplasms is used; (3)With fractures, dislocations, etc.; with severe diseases such as tumors, cardiovascular and cerebrovascular diseases, and hematopathy,with mental illness and communication disorders that efficacy cannot be determined.Additionally pain and mobility disorder related to other conditions(eg,internal organs lesion,cardiovascular and cerebrovascular diseases ) ; (4)Pregnant, Lactating women,or women of childbearing age who are preparing to conceive; (5)With other conditions that the researchers deems inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total effective rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale;Western Ontario and McMaster University Osteoarthritis Index (WOMAC) ;Lysholm Knee Scoring Scale;satisfaction and comfort of Cataplasms; | — |
Countries
China
Contacts
Public ContactLin Guo
Affiliated Zhongshan Hospital of Dalian University
Outcome results
None listed