Dentition defects
Conditions
Interventions
0~40Gy group:0~40Gy
40~45Gy group:40~45Gy
45~50Gy group:45~50Gy
Sponsors
Shanghai Ninth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) The age of the patient must be >=18 years; 2) Receiving radiotherapy for the head and neck alone or postoperative radiotherapy, with or without chemotherapy; 3) Partially or completely edentulous, with implant restoration needs and meeting the indications for implant restoration; 4) The dose of potential dental implant is not more than 50Gy and 12 months or more after radiotherapy; 5) Subjects voluntarily sign the informed consent form prior to the implementation of any study-related trial steps.
Exclusion criteria
Exclusion criteria: 1) The potential dental implant is reconstructed after partial removal of the jaw; 2) Absolute and relative contraindications to implant surgery, systemic diseases affecting osseointegration, wound healing and dental implant treatment: such as uncontrolled and stable diabetes mellitus and hypertension; Grade II and above cardiac disease; Patients with abnormal liver and kidney function; Immunocompromised; obese patients; Patients taking drugs that affect the effectiveness of treatment: such as patients on long-term high-dose steroid therapy; Patients who have been treated with drugs (such as bisphosphonates) that may affect or promote bone metabolism within the past 3 months, etc.; 3) Smoking/tobacco equivalents/chewing tobacco more than 10 per day; 4) Other special populations: such as physical or mental impairments that affect oral health care; Patients with product allergies; Female patients who are pregnant or breastfeeding, etc.; 5) Patients who are considered by the investigator to have poor compliance and cannot participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival rate; | — |
Countries
China
Contacts
Public ContactYu Dedong
Shanghai Ninth People's Hospital
Outcome results
None listed