morbidly obese
Conditions
Interventions
Experimental group:Induction of general anesthesia with ciprofol
Sponsors
Lishui People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 65 (both male and female); 2. The American Society of Anesthesiologists (ASA) grade II-III; 3. BMI >= 35 kg/m^2; 4. Can understand the procedures and methods of this study, willing to sign an informed consent form and strictly follow the clinical research protocol to complete this study.
Exclusion criteria
Exclusion criteria: 1. Patients with preoperative neurological or psychiatric disorders or communication disorders; 2. Allergic to the drugs used in this study; 3. Long term preoperative use of benzodiazepines and opioids; 4. Patients with severe arrhythmia, such as second or third degree atrioventricular block or significant bradycardia (HR<50 beats/minute); 5. New York Heart Association (NYHA) cardiac function class III or IV; 6. Participants who have participated in any clinical trials as subjects within the first month of enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 50% and 95% effective dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse event; | — |
Countries
China
Contacts
Public ContactDuan gongchen
Lishui People's Hospital
Outcome results
None listed