Skip to content

The effect of dexmedetomidine combined with ketamine on reducing opioid use and postoperative recovery quality during gynecological laparoscopic surgery

The effect of dexmedetomidine combined with ketamine on reducing opioid use and postoperative recovery quality during gynecological laparoscopic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094281
Enrollment
Unknown
Registered
2024-12-19
Start date
2024-12-24
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynaecology

Interventions

Dexmedetomidine group (D group):All patients in this group received standardized total intravenous anesthesia. In the Dexmedetomidine group (Group D), 1 ug/kg of dexmedetomidine was infused over 10-15

Sponsors

The Second Hospital of Sanming City, Fujian Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA Classification I.-III; 2. Age 18-65 years old; 3.BMI 18.5-30kg/?; 4. Laparoscopic total hysterectomy, laparoscopic myomectomy, sub-abdominal adnexal mass exfoliation, etc.; 5. Able to understand the content of the assessment scale.

Exclusion criteria

Exclusion criteria: 1. Those who do not understand or refuse the test method; 2. Those suffering from mental disorders, anxiety disorders, and depression; 3. Those who suffer from insomnia, abuse of drugs or alcohol, use of benzodiazepines, or drugs; 4. Patients with severe heart, liver, kidney and other chronic diseases, abnormal coagulation function; 5. Intraoperative transfer to laparotomy or the operation method is changed to extensive abdominal lymphatic dissection. 6. Patients with contraindications to the use of drugs related to this study (esketamine, dexmedetomidine). 7. After completing the basic laboratory examination, the anesthesiology research group physician will evaluate the patients with contraindications to surgical anesthesia.

Design outcomes

Primary

MeasureTime frame
Remifentanil usage;Number of postoperative vomiting episodes;Anxiety Depression Scale;

Secondary

MeasureTime frame
Blood pressure;Heart rate;

Countries

China

Contacts

Public ContactShi Xiaohong

The Second Hospital of Sanming City, Fujian Province

381141774@qq.com+86 159 6095 1252

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026